February 22 is National Margarita Day, a day designated for the celebration of all things tequila, triple sec and lime. While the famous cocktail has been around for less than a century, it's become a staple at restaurants and bars around the world, with each establishment adding its own unique twist. Since your hangover is likely to last longer than this annual holiday, feel free to celebrate all year long.

Cancun is undoubtedly a bucket-list destination for margarita lovers and visitors to Mexico's Yucatan Peninsula will find multiple versions of the nectarous cocktail at the all-inclusive Hyatt Ziva Cancun. The resort's Juana Margarita tequila bar is home to more than 25 different types of tequila and expert mixologists are on hand to craft margaritas and other cocktails while sharpening guests' knowledge of the iconic libation.

Elsewhere in Cancun, the adults-only Le Blanc Spa Resort is the ideal place to reset your palate with a refreshing margarita. The resort's many bars range from casual to chic and guests can enjoy a cocktail in the lobby, by the pool, on the beach or even in their room thanks to 24-hour room service.

The newly-redesigned TRS Yucatan Hotel in Mexico's Riviera Maya certainly isn't short on bars with 22 located throughout the complex. That said, guests are all but certain to find a margarita that suits their taste.

Believe it or not, stellar margaritas do exist outside of Mexico and the innovative Sandals LaSource Grenada is a great place to begin your search for the Caribbean's best. After all, the all-inclusive resort along Pink Gin Beach features half of a dozen bars offering guests unlimited premium spirits.

The Barcelo Grand Faro Los Cabos features a robust selection of margaritas at its Las Jicamas Mexican Bar and Restaurant. Better yet, guests can purchase the all-inclusive plan and try them all without having to pick up the check.

Whether you want to be entertained, relax or just watch the game, Playa del Carmen's Sandos Caracol Eco Resort has a bar for you. Guests can unwind with a margarita at the open-air Raccoon chill-out bar, enjoy a cocktail and a show at the theater bar or pair their libation with live sports at The Mangrove.

For a top-flight margarita in Mexico's Jalisco state, head to Puerto Vallarta. The all-inclusive Hyatt Ziva resort here boasts more than a dozen bars, restaurants and lounges, including a walk-up or swim-up pool bar and a hacienda-style tequila sports bar.

Riviera Maya's new Hotel Xcaret is another excellent choice for travelers who are passionate about their margaritas. Featuring eight different bars to choose from, guests can sip their cold drink in the lobby, in the pool or even on the roof. The adults-only Cantina Los Faroles is also a must-visit for fans of the beloved Mexican concoction.

The adults-only, all-inclusive Sian Ka'an at Grand Tulum offers guests 11 bars, including two swim-up bars. The Sarape Tequila Bar is an excellent starting point for margarita connoisseurs. However, there are numerous opportunities to expand your horizons at the Martini Piano Bar and Sensoria Champagne Bar.

Few cities on the planet consume cocktails quite like New Orleans. If you love a well-crafted margarita, make the Royal Sonesta New Orleans your base camp on your next trip to the Big Easy. The AAA Four Diamond-rated Bourbon Street hotel features multiple on-site bars, including Bar R'evolution, which serves up a variety of signature cocktails. Take a break from the margarita without ditching the tequila via the "Red Sky at Night."